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Search Results for " escherichia coli "

90

抑制剂 & 化合物

41

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14864	Caracemide NSC-253272,卡醋胺	Others; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Caracemide (NSC-253272) 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
T33828	O-Succinylhomoserine O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine	Others	Others
	O-Succinylhomoserine (O-Succinyl-L-homoserine) 是大肠杆菌合成胱硫醚的中间体。
T36683	Vedaprofen Quadrisol,PM 150,维达洛芬,CERM 10202	COX; Antibacterial; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Vedaprofen (PM 150) 抑制 COX-1 并通过抗炎活性减少前列腺素 H2 的合成。 Vedaprofen 是一种大肠杆菌滑动钳抑制剂，IC50 为 222 μM，Ki 为 131 μM。
T1224	Cefuroxime sodium Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin	Antibacterial; Antibiotic	Microbiology/Virology
	Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素，增加了对 β-内酰胺酶的稳定性。
T0909L	Nalidixic acid sodium salt 萘啶酮酸,萘啶酮酸钠,Baktogram,Sodium nalidixate	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Nalidixic acid sodium salt (Baktogram) 是一种喹诺酮类抗生素，对革兰氏阳性和革兰氏阴性细菌均有效。它在较低浓度下有抑菌作用，在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。
T0788L	Spectinomycin dihydrochloride pentahydrate 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素，可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。
T6179	Moxalactam sodium salt Latamoxef sodium,6059 S,拉氧头孢钠,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy	Antibacterial; Antibiotic	Microbiology/Virology
	Moxalactam sodium salt (LY-127935) 是一种抗生素, 对大肠杆菌和绿脓杆菌有作用。
T8629	N-BENZYL-2-PHENYLETHYLAMINE	Others	Others
	N-BENZYL-2-PHENYLETHYLAMINE 是 rel+ Escherichia coli B Phe-tRNA 的抑制剂。
T60093	CHEMBL1380345 N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)	Antibacterial	Microbiology/Virology
	CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性，pMIC 值分别为 3.64、3.56 和 3.70。
T33470	Monoctanoin 辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin	Antibacterial	Microbiology/Virology
	Monoctanoin (Glyceryl 1-caprylate) 对金黄色葡萄球菌和大肠杆菌具有抗菌活性。
T10347L	Apidaecin IB acetate Apidaecin IB acetate (123276-94-8 Free base)	Others	Others
	Apidaecin IB acetate 是一种昆虫抗菌肽。 apidaecin IB acetate 对大肠杆菌（大肠杆菌 ML35、o18k1h7 和 ATCC 25922）的有效浓度为 8 μM。
T38137	3,5-Dimethylbenzaldehyde	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	3,5-Dimethylbenzaldehyde 具有广谱的抗菌活性，对枯草芽孢杆菌、白假丝酵母菌、大肠杆菌、铜绿假单胞菌、金黄色葡萄杆菌和肺炎链球菌具有抑制作用。
T3175	LDHA-IN-4 AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase	Metabolism
	LDHA-IN-4 (AZ33) 是乳酸脱氢酶 A 选择性抑制剂，IC50=0.5 μM，Kd=0.093 μM。
T67928	NDH-1 inhibitor-1	Mitochondrial Metabolism	Metabolism
	NDH-1 inhibitor-1 是一种有效的 NDH-1 抑制剂，对牛 SMP (线粒体颗粒)，马铃薯 SMP 和大肠杆菌的 pI50 值分别为 <4, 5.40, 6.15 µM。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T41274	p-Fluoro-L-phenylalanine	Hydroxylase	Metabolism
	p-Fluoro-L-phenylalanine 是酪氨酸羟化酶的一种底物。它可以与大肠杆菌的 L-亮氨酸特异性受体结合，KD 为0.26 μM。
T77608	1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-	Antifungal	Microbiology/Virology
	1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 可作为一种广谱抗菌剂，对黑曲霉枯草芽孢杆菌、白假丝酵母、大肠杆菌和金黄色葡萄球菌有抑制作用。1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 在体外实验中显示出抗炎活性，可用于治疗细菌感染。
T40376	L-Phenylalanine-15N L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
T29919	Altronic acid
	Altronic acid comes from Escherichia coli.
T20751	Carumonam
	Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.
T26579	AHU1
	AHU1 is a blocker of Shiga Toxin expression in Escherichia coli O157:H7.
T38567	STh
	STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.
T31475	Dihydropteroyl hexaglutamate
	Dihydropteroyl hexaglutamate is a link binding together sub-structures of the tail of Escherichia coli bacteriophage T4.
T25733	Lincophenicol
	Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.
T69372	Cyclamidomycin
	Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.
T64135	Antibacterial agent 68
	Antibacterial agent 68 是一种针对耐药 Escherichia coli 的抗菌剂，具有低细胞毒性。Antibacterial agent 68 在 0.007 mM 的低浓度下能够强烈抑制多重耐药的 Escherichia coli 的活性。
T30826	Cgp 31523A Cgp-31523A,Cgp31523A
	CGP 31523a is a new type of aminothiazolyl cephalosporin, which can inhibit Escherichia coli, Klebsiella pneumoniae, Pseudomonas mirabilis, Clostridium diving, Klebsiella acidogenes, Pseudomonas Stuart, Salmonella, and Shigella.
T29882	Allolactose
	Allolactose is a disaccharide used as an inducer of the lac operon in Escherichia coli and many other enteric bacteria.
T80413	Bass hepcidin
	Bass hepcidin是一种具有针对大肠埃希菌活性的抗菌肽。
T71535	GlmU-IN-5175178
	GlmU-IN-5175178 is an inhibitor of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).
T61368	FPI-1602
	FPI-1602 is a β-lactamase inhibitor with strong antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, and Enterobacter species [1].
T39296	DS86760016
	DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Notably, DS86760016 effectively inhibits LeuRS enzymes derived from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, exhibiting IC50 values of 0.38 μM, 0.62 μM, and 0.16 μM, respectively.
T28807	SLUPP-225 SLUPP 225
	SLUPP-225 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T63449	MsbA-IN-3
	MsbA-IN-3 是一种有效的、高度选择性的 MsbA 抑制剂 (IC50: 2 nM)。MsbA-IN-3 能够抑制大肠杆菌 (Escherichia coli) 的活性 (MIC: 35 μM)。
T80323	Bovine neutrophil beta-defensin 12 BNBD-12
	Bovine neutrophil beta-defensin 12，一种牛中性粒细胞来源的抗菌肽，展现针对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)的抗菌活性。
T68203	Tuberine, (+)-
	Tuberine, (+)- is an alkaloid isolated from Haplophyllum tuberculatum that has high antimicrobial activity against Staphylococcus aureus, Bacillus subtilis and Saccharomyces cerevisiae. Tuberine, (+)- is also slightly inhibitory to Escherichia coli .
T28808	SLUPP-417 SLUPP417
	SLUPP-417 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T40433	D-Cystine
	D-Cystine, the D-enantiomer of L-Cystine, functions as an inhibitor of L-aspartate-β-semialdehyde dehydrogenase (ASADH) derived from Escherichia coli.
T63033	MsbA-IN-4
	MsbA-IN-4 (compound 32) 是一种高度选择性的、有效的 MsbA 抑制剂 (IC50: 3 nM)。MsbA-IN-4 能够抑制大肠杆菌 (Escherichia coli) (MIC: 12 μM)。
T80398	Brevinin-1PMa
	Brevinin-1PMa为宿主防御肽，对金黄色葡萄球菌（Staphylococcus aureus）和大肠杆菌（Escherichia coli）展现出抗菌活性，并具溶血活性。
T73531	SABA1
	SABA1 具有抗菌活性，比如铜绿假单胞菌和大肠杆菌，其对大肠杆菌的IC50值为 4.0 µM。
T80317	Combi-2
	Combi-2为针对S.aureus、S.sanguis及E.coli具有抗菌活性的肽类化合物。
T80339	Gallin
	Gallin是一种从蛋清提取的抗菌肽，在0.25 µM浓度时能够抑制Escherischia coli的生长。
T80447	Pardaxin P5
	Pardaxin P5，一种抗菌肽，其对大肠杆菌的最小抑制浓度（MIC）为13 μM。
T80411	Bactenecin 5
	Bactenecin 5是一种具有抗菌活性的牛抗菌肽，能够针对Escherichia coli、Salmonella typhimurium和Klebsiella pneumoniae. T发挥作用，其最小抑菌浓度（MIC）介于12-25 μg/mL之间。
T81157	SIGSLAK
	SIGSLAK 拥有与大肠杆菌青霉素结合蛋白 1b (PBP1b) 活性位点相对应的结构特征。
T10944	D13-9001	Others	Others
	The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor.
T68438	APO-6619
	APO-6619 is an iron chelator which was shown to inhibit growth of the following bacterial strains: Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli. APO-6619 may be useful as a non-traditional treatment of bacterial infections.
T61251	Antibacterial agent 97
	Antibacterial agent 97 (hit compound) 是一种有效的抗菌剂。Antibacterial agent 97 对大肠杆菌(E.coli)和金黄色酿脓葡萄球菌 (S.aureus)的 MIC 分别为 16 和 16 μg/mL[1]。
T77237	N,O-Didansyl-L-tyrosine cyclohexylammonium
	N,O-Didansyl-L-tyrosine cyclohexylammonium 是一种有效的选择性胸苷酸合成酶 (TS) 抑制剂，作用于Escherichia coli，Lactobacillus casei 和人的 TS 的IC50值分别是 5.0，3.4 和 119 μM。

化合物

Cat.No: T14864

Synonym: NSC-253272,卡醋胺

Target: Others, DNA/RNA Synthesis, Antibacterial

O-Succinylhomoserine

Cat.No: T33828

Synonym: O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine

Target: Others

Cat.No: T36683

Synonym: Quadrisol,PM 150,维达洛芬,CERM 10202

Target: COX, Antibacterial, Prostaglandin Receptor

Cefuroxime sodium

Cat.No: T1224

Synonym: Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin

Target: Antibacterial, Antibiotic

Nalidixic acid sodium salt

Cat.No: T0909L

Synonym: 萘啶酮酸,萘啶酮酸钠,Baktogram,Sodium nalidixate

Target: Topoisomerase, Antibacterial, Antibiotic

Spectinomycin dihydrochloride pentahydrate

Cat.No: T0788L

Synonym: 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

Moxalactam sodium salt

Cat.No: T6179

Synonym: Latamoxef sodium,6059 S,拉氧头孢钠,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy

Target: Antibacterial, Antibiotic

N-BENZYL-2-PHENYLETHYLAMINE

Cat.No: T8629

Target: Others

Cat.No: T60093

Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)

Target: Antibacterial

Cat.No: T33470

Synonym: 辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin

Target: Antibacterial

Apidaecin IB acetate

Cat.No: T10347L

Synonym: Apidaecin IB acetate (123276-94-8 Free base)

Target: Others

3,5-Dimethylbenzaldehyde

Cat.No: T38137

Target: Endogenous Metabolite, Antifungal

Cat.No: T3175

Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33

Target: Dehydrogenase

NDH-1 inhibitor-1

Cat.No: T67928

Target: Mitochondrial Metabolism

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

p-Fluoro-L-phenylalanine

Cat.No: T41274

Target: Hydroxylase

1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-

Cat.No: T77608

Target: Antifungal

L-Phenylalanine-15N

Cat.No: T40376

Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Target: Calcium Channel

Cat.No: T29919

Cat.No: T20751

Cat.No: T26579

Cat.No: T38567

Dihydropteroyl hexaglutamate

Cat.No: T31475

Cat.No: T25733

Cat.No: T69372

Antibacterial agent 68

Cat.No: T64135

Cat.No: T30826

Synonym: Cgp-31523A,Cgp31523A

Cat.No: T29882

Cat.No: T80413

GlmU-IN-5175178

Cat.No: T71535

Cat.No: T61368

Cat.No: T39296

Cat.No: T28807

Synonym: SLUPP 225

Cat.No: T63449

Bovine neutrophil beta-defensin 12

Cat.No: T80323

Synonym: BNBD-12

Cat.No: T68203

Cat.No: T28808

Synonym: SLUPP417

Cat.No: T40433

Cat.No: T63033

Cat.No: T80398

Cat.No: T73531

Cat.No: T80317

Cat.No: T80339

Cat.No: T80447

Cat.No: T80411

Cat.No: T81157

Cat.No: T10944

Target: Others

Cat.No: T68438

Antibacterial agent 97

Cat.No: T61251

N,O-Didansyl-L-tyrosine cyclohexylammonium

Cat.No: T77237

Cat. No.	Product Name	Target	Signaling Pathways
T2904	Sclareolide 香紫苏内酯,Norambreinolide	Others; Antibacterial	Microbiology/Virology; Others
	Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物，具有抗菌和细胞毒性作用。
T0909	Nalidixic acid 萘啶酸,NSC-82174	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Nalidixic acid (NSC-82174) 是一种喹诺酮类抗生素，对革兰氏阳性和革兰氏阴性细菌有效。它在较低浓度下有抑菌作用，而在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。
T0788	Spectinomycin dihydrochloride 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。
T7565	3-Hydroxycapric acid	Endogenous Metabolite	Metabolism
	3-Hydroxycapric acid 是有丝分裂抑制剂。
T10941	D-Ribonolactone D-(+)-核糖酸-1,4-内酯,D-核糖内酯	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Ribonolactone 是一种大肠杆菌 β-半乳糖苷酶的抑制剂，Ki 为 26 mM。它也一种糖内酯。
T13750	L-Fucitol L-岩藻糖醇,1-Deoxy-D-galactitol	Others	Others
	L-Fucitol (1-Deoxy-D-galactitol) 是一种糖醇，从肉豆蔻 (Nutmeg) 中分离得到。
TF0083	POPE
	POPE 是从大肠杆菌中发现的化合物，是细胞膜的一部分，可用来研究改变细胞膜通透性。
T6S2116	Ginkgolic acid C17:1 银杏酸 C17:1,银杏酸C17:1	Phosphatase; PTEN	Metabolism; PI3K/Akt/mTOR signaling
	Ginkgolic acid C17:1 是分离自银杏叶中，通过诱导PTEN 和SHP-1酪氨酸磷酸酶抑制组成型和诱导型 STAT3 活化。它具有抗癌活性。
T5055	For-Met-OH fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine	Others; Endogenous Metabolite	Metabolism; Others
	For-Met-OH (N-Formyl-L-methionine) 是内源性代谢产物的一种。
T5244	Aminomalonic acid 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate	Others; Endogenous Metabolite	Metabolism; Others
	Aminomalonic acid (Aminomalonate) 是氨基内源性代谢产物，在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的 L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M，小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
TN7224	2,2'-Dihydroxy chalcone	Antibacterial; Autophagy	Autophagy; Microbiology/Virology
	2,2'-Dihydroxy chalcone 是一种用 fMLP/CB 刺激的大鼠中性粒细胞释放β-葡糖醛酸酶（IC50=1.6±0.2μM）和溶菌酶（IC50=1.4±0.2μM）的有效抑制剂。2,2'-Dihydroxy chalcone 对大肠杆菌、福氏志贺氏菌、白葡萄球菌和金黄色葡萄球菌有抑菌活性。
T2S0493	Isoeugenol 4-Propenylguaiacol,2-Methoxy-4-propenylphenol,异丁香酚,异丁香酚;4-丙烯基-2-甲氧基苯酚、对丙烯基邻甲氧基本酚、异丁子香酚	Antibacterial	Microbiology/Virology
	Isoeugenol (4-Propenylguaiacol) 是肉豆蔻，丁香和肉桂的精油成分，具有抗菌活性。它抑制Escherichia coli 和Listeria innocua，MIC 值分别为 0.6 mg/mL 和 1 mg/mL。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
TN4927	Rupesin E	Antifection	Microbiology/Virology
	Rupesin E shows significant antibacterial activities against Escherichia coli.
T72250	4aα,7α,7aα-Nepetalactone
	4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性，抑制Escherichia coli，Pseudomonas aeruginosa，Staphylococcus aureus，Salmonella typhi 和Enterococcus faecalis。
T26747	BB-3497 BB 3497,BB3497
	BB-3497, a potent inhibitor of Escherichia coli peptide deformylase, has antibacterial activity both in vitro and in vivo.
TN2820	24-Methylenecycloartan-3-ol	Antifection	Microbiology/Virology
	24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.
TN2760	2-Hydroxy-1,8-cineole	Antifection	Microbiology/Virology
	1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .<BR/>
TN1203	2,3,8-Tri-O-methylellagic acid 2,3,8-三邻甲基鞣花酸	Antifection	Microbiology/Virology
	2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli.
T40529	(R)-(-)-1,2-Propanediol
	(R)-(-)-1,2-Propanediol is the (R)-enantiomer of 1,2-Propanediol, which is derived from glucose through the expression of NADH-linked glycerol dehydrogenase genes in Escherichia coli.
TN4579	Monomethylsulochrin	Antifection	Microbiology/Virology
	Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effects on the human bacterial pathogen Helicobacter pylori with the MIC value of 28.9+/-0.1 microM.
T40814	Colominic acid sodium salt Polysialic acid sodium salt,Colominic acid sodium salt
	Colominic acid sodium salt, also known as polysialic acid sodium salt, is naturally isolated from the cell wall of Escherichia coli and animals. It exhibits a red color with an absorption maximum of 530 nm and possesses anti-bacterial activity.
T80354	Maximin 39
	Maximin 39为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌（Staphylococcus aureus）和大肠杆菌（Escherichia coli）的活性，其最小抑菌浓度（MIC）值分别为18.8 μg/mL和37.5 μg/mL。
TN3400	Altechromone A	Antifection	Microbiology/Virology
	Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
T80351	Maximin 28
	Maximin 28为源自蟾蜍大脑的抗菌肽，对金黄色葡萄球菌(Staphylococcus aureus)、大肠杆菌(Escherichia coli)及枯草芽孢杆菌(Bacillus subtilis)表现出抗菌活性，其MIC值分别为4.7、9.4、75 μg/mL。
TN4731	Pachyaximine A	Antifection	Microbiology/Virology
	Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. (-)-Pachyaximine A demonstrates significant activity as antiestrogen binding site (AEBS
T80335	Maximin H3
	Maximin H3，源自中华红腹蟾蜍Bombina maxima皮肤分泌，为一种抗菌肽。对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 2592、Bacillus pyocyaneus CMCC B1010 及Candida albicans ATCC 2002表现出显著抗性，其MIC值依次为20, 10, 20, 5 μg/ml。
TN3403	Djalonensone 交链孢霉甲基醚,Alternariol monomethyl ether	Immunology/Inflammation related	Immunology/Inflammation
	Djalonensone (Alternariol monomethyl ether) 具有强大的 DPPH 自由基清除作用。
T80349	Maximin H4
	Maximin H4是一种来自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，具有针对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010和Candida albicans ATCC2002的抗菌活性。其最小抑菌浓度(MIC)值依次为12、6、12、6 μg/ml。
T80001	Majoranaquinone	Antibiotic	Microbiology/Virology
	Majoranaquinone对4种Staphylococcus菌株、1种Moraxella菌株和1种Enterococcus菌株显示出良好的抑菌作用。此外，Majoranaquinone在E.coli ATCC 25922菌株中表现出显著的外排泵抑制活性，并能有效抑制E.coli ATCC 25922和E.coli K-12 AG100的生物膜形成。
T80334	Maximin H2
	Maximin H2，源自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010及Candida albicans ATCC2002展示了明显的抗菌活性。其最小抑菌浓度(MIC)值依序为20、2、4、2 μg/ml。
T80332	Maximin H1
	Maximin H1是一种抗菌肽，由中华红腹蟾蜍(Bombina maxima)皮肤分泌物提取得到。该化合物对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 25923、Bacillus pyocyaneus CMCC B1010和Candida albicans ATCC 2002表现出抗菌活性，其最小抑菌浓度(MIC)值分别为9、4.5、9、4.5 μg/ml。
T80355	Bombinin H1
	Bombinin H1是Bombina variegata蛾皮肤中提取的抗菌肽。该肽对大肠杆菌D21的致死浓度为3.8μM，而对金黄色葡萄球菌Cowan 1的致死浓度为2.1μM。
T80358	Bombinin H3
	Bombinin H3为源自蛾Bombina variegata皮肤的抗菌肽。其对大肠杆菌D21的致死浓度为3.7 μM，而针对金黄色葡萄球菌Cowan 1的致死浓度为2.4 μM。
TN2626	14-Norpseurotin A	Antifection	Microbiology/Virology
	14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 microM , r
T80350	Maximin 15
	Maximin 15为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌的活性，其最小抑菌浓度(MIC)值依次为9.4, 18.8, 75 μg/mL。
T79986	Brevianamide M
	Brevianamide M (compound 4)为Aspergillus versicolor代谢物，该物质源自海洋褐藻Ecklonia马尾藻中分离的内生真菌。Brevianamide M展示出针对大肠杆菌和金黄色葡萄球菌的抗菌活性。
T80353	Maximin 32
	Maximin 32 是源于蟾蜍大脑的抗菌肽，对金黄色葡萄球菌和大肠杆菌表现出活性，其 MIC 值分别为 9.4 和 18.8 μg/mL。
T80360	Bombinin H4
	Bombinin H4，蛾Bombina variegata皮肤中的抗菌肽，其对大肠杆菌D21和金黄色葡萄球菌Cowan 1的致死浓度分别为4.8 μM和3.3 μM。
T80352	Maximin 31
	Maximin 31 是抗菌肽，源自蟾蜍大脑。该化合物对金黄色葡萄球菌和大肠杆菌表现出抗菌活性，其最小抑菌浓度（MIC）值分别为 37.5 μg/mL 和 75 μg/mL。
TN4402	Labd-13-ene-8,15-diol	Antifection	Microbiology/Virology
	13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits antilung and antilaryngeal cancer ac

天然产物

Cat.No: T2904

Synonym: 香紫苏内酯,Norambreinolide

Target: Others, Antibacterial

Cat.No: T0909

Synonym: 萘啶酸,NSC-82174

Target: Topoisomerase, Antibacterial, Antibiotic

Spectinomycin dihydrochloride

Cat.No: T0788

Synonym: 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

3-Hydroxycapric acid

Cat.No: T7565

Target: Endogenous Metabolite

D-Ribonolactone

Cat.No: T10941

Synonym: D-(+)-核糖酸-1,4-内酯,D-核糖内酯

Target: Endogenous Metabolite, Antibacterial

Cat.No: T13750

Synonym: L-岩藻糖醇,1-Deoxy-D-galactitol

Target: Others

Cat.No: TF0083

Ginkgolic acid C17:1

Cat.No: T6S2116

Synonym: 银杏酸 C17:1,银杏酸C17:1

Target: Phosphatase, PTEN

Cat.No: T5055

Synonym: fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

Aminomalonic acid

Cat.No: T5244

Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Target: Others, Endogenous Metabolite

2,2'-Dihydroxy chalcone

Cat.No: TN7224

Target: Antibacterial, Autophagy

Cat.No: T2S0493

Synonym: 4-Propenylguaiacol,2-Methoxy-4-propenylphenol,异丁香酚,异丁香酚;4-丙烯基-2-甲氧基苯酚、对丙烯基邻甲氧基本酚、异丁子香酚

Target: Antibacterial

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

Cat.No: TN4927

Target: Antifection

4aα,7α,7aα-Nepetalactone

Cat.No: T72250

Cat.No: T26747

Synonym: BB 3497,BB3497

24-Methylenecycloartan-3-ol

Cat.No: TN2820

Target: Antifection

2-Hydroxy-1,8-cineole

Cat.No: TN2760

Target: Antifection

2,3,8-Tri-O-methylellagic acid

Cat.No: TN1203

Synonym: 2,3,8-三邻甲基鞣花酸

Target: Antifection

(R)-(-)-1,2-Propanediol

Cat.No: T40529

Monomethylsulochrin

Cat.No: TN4579

Target: Antifection

Colominic acid sodium salt

Cat.No: T40814

Synonym: Polysialic acid sodium salt,Colominic acid sodium salt

Cat.No: T80354

Cat.No: TN3400

Target: Antifection

Cat.No: T80351

Cat.No: TN4731

Target: Antifection

Cat.No: T80335

Cat.No: TN3403

Synonym: 交链孢霉甲基醚,Alternariol monomethyl ether

Target: Immunology/Inflammation related

Cat.No: T80349

Majoranaquinone

Cat.No: T80001

Target: Antibiotic

Cat.No: T80334

Cat.No: T80332

Cat.No: T80355

Cat.No: T80358

14-Norpseurotin A

Cat.No: TN2626

Target: Antifection

Cat.No: T80350

Cat.No: T79986

Cat.No: T80353

Cat.No: T80360

Cat.No: T80352

Labd-13-ene-8,15-diol

Cat.No: TN4402

Target: Antifection

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